Sorbitan monolaurate structure. Polysorbate 20 mber 1, 2014 .

Sorbitan monolaurate structure. 1 The chemical structure of Tween 20 (Polysorbate 20). Uses Lonzest (R) SML is used as a lubricant and as an emulsifier. 2 and reflect results obtained ante - and post -hydrolysis, whereas the values on the third row represent the theoretical values based on the molecular structure of polyethylene glycol (20) sorbitan monolaurate. Mar 29, 2024 · Sorbitan Laurate is a partial monoester of natural lauric acid (a fatty acid with a 12-carbon backbone) and sorbitan (cyclic ether produced by the dehydration of the hexahydric alcohol - sorbitol). AI generated definition based on: Databook of the Most Important Polymer and Rubber Additives, 2024 This substance record has relationships which can be visualized as a network with other substance records. Solvent— Use dimethyl sulfoxide. This process is also known as ethoxylation. ] Sorbitan, esters, mono (Z)-9-octadecenoate. Span® 20 for synthesis. Span-20 emulsifier is a mixture of esters from fatty acid, lauric acid, and polyols derived from sorbitol, including sorbitan and Aug 1, 2008 · Polysorbates 20 and 80 (Tween® 20 and Tween® 80) are used in the formulation of biotherapeutic products for both preventing surface adsorption and as stabilizers against protein aggregation. 493 A mixture of the partial esters of sorbitol and its mono- and dianhydrides with edible lauric acid 1338-39-2 Contains lauric acid esterified with polyols derived from sorbitol including the following types: Download scientific diagram | Structural formula of sorbitan monolaurate from publication: Safety and efficacy of sorbitan monolaurate as a feed additive for all animal species | The additive Span (R) 20 | C18H34O6 | CID 16218599 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities Sorbitan is a mixture of isomeric organic compounds derived from the dehydration of sorbitol and is an intermediate in the conversion of sorbitol to isosorbide. Sorbitan monododecanoate | C18H34O6 | CID 11046239 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological Jul 3, 2013 · Polyoxyethylene (20) sorbitan monolaurate (INCI: Polysorbate 20), is a ubiquitous nonionic surfactant employed in the formulation of countless cosmetic and personal care products. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative Chemical-Physical Properties: Polysorbate 20 is a nonionic surfactant composed of sorbitan, lauric acid, and ethoxylated chains. 0g of potassium hydroxide,and mix. Sorbitan Monolaurate | C18H34O6 | CID 11046239 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Tween 20 (Polysorbate 20) is a versatile non-ionic surfactant used in food, pharmaceuticals, and cosmetics for emulsification and solubilization. Polysorbate 20 (Tween 20) chemical structure. The molecular structure is based on structures generated from information available in ECHA’s databases. Spectral Data Sorbitan monolaurate mass spectral data can be found in a separate interface. Sorbitan monododecanoate can be used as an excipient, such as nonionic surfactants, emulsifiers. Monolaurate is indicated by 20 Sorbitan mono- (9Z)-9-octadecenoate | C24H44O6 | CID 9920342 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Fatty acid constituents of this product are determined by transesterification to yield fatty acid me yl esters which are identified by gas chromatography. [2] As a food additive, it is designated with the E number E493. It is also used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions. The European food additive number for it is E432. 3, suggesting poor dispersion characteristics in water and relatively low monomer solubility for the latter. AI generated definition based on: Studies in Surface Science and Catalysis, 2001 Polysorbate 20 (Sorbitan monolaurate 20 EO) functions as an emulsifier in products such as salad dressings, sauces, desserts, and ice creams, helping to stabilize oil-in-water emulsions and prevent ingredient separation. Nov 5, 2024 · Abstract In order to develop a lamellar liquid crystal system consisting of temperature-insensitive and mild non-ionic surfactants, we construct the phase diagram of sucrose laurate (L1695)/sorbitan monolaurate (Span 20)/water pseudo-ternary systems at 25 ℃ based on the direct visual inspection and polarized microscopy. Interfacial properties of the surfactants were determined using a du Nouy tensiometer and rheological properties of selected creams with oscillation stress sweep The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. Additionally, Polysorbate 20 (Sorbitan monolaurate 20 EO) is used in baked goods to improve texture and moisture retention. It yields, upon saponification, NLT 55. Fig. Oct 26, 2020 · Commercially available PS20 and PS80 are chemically diverse mixtures, 2 and the expected structure for PS20 (polyoxyethylene (20) sorbitan monolaurate) and PS80 (polyoxyethylene (80) sorbitan monooleate) only accounts for 20% of the total polysorbate. 9 The heterogeneity arises not only from the hydrophilic head group and fatty acid tail, but ChemSpider record containing structure, synonyms, properties, vendors and database links for 1,4-Sorbitan, 27299-12-3, JNYAEWCLZODPBN-JGWLITMVSA-N May 15, 2020 · Learn more about the emulsifier - Sorbitan monostearate (E491), from production, uses in food and yeast, safety, and some FAQS. As a synthetic non-ionic surfactant and emulsifier, it’s derived from sorbitol, a sugar alcohol. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. (Last updated: 2023-11-01) Feb 14, 2024 · Sorbitan Laurate is a colorless, liquid surfactant commonly added to cosmetics and personal care products. Oct 24, 2002 · Creams from three components, surfactant, purified water and oil, were prepared. 0% of fatty acids, and NLT 39. 46, density about 1,030 kg/m 3). Of the sugar esters listed in Table 1, sorbitan monolaurate has the highest monomer solubility, the form responsible for membrane insertion. Sorbitan monolaurate is a mixture of esters formed from the fatty acid lauric acid and polyols derived from sorbitol, including sorbitan and isosorbide. Sorbitan monolaurate, also known as Span 20, is defined as a food-grade surfactant used in emulsions, characterized by its hydrophilic-lipophilic balance (HLB) of 8. Mar 27, 2019 · The predominant structure is sorbitan monolaurate, from which the additive derives its name (synonyms: sorbitan laurate, sorbitan monododecanoate; Chemical Abstract Service (CAS) number 1338-39-2 and EINECS number 215-663-3; molecular weight 346. Comparable molar fractions of components were used in order to better understand the structural properties of the components used. Apr 23, 2020 · Polysorbate 20 or Tween 20, the abbreviation of “polyoxyethylene (20) sorbitan monolaurate”, is a nonionic surfactant and an emulsifier used much in cosmetics than in food. 6 and for the longer chain sorbitan oleate, the HLB is 4. Sorbitan Monostearate (Span 60) Sorbitan Monostearate, also known as SMS or Span 60, is a chemical compound synthesized from sorbitan esterified with stearic acid. It is used as an additive in food, pharmaceuticals and cosmetics. [1] Oct 28, 2025 · Sorbitan monostearate is a partial ester of stearic acid with sorbitol and its mono- and dianhydrides. The sorbitan monolaurate/polyox… Jun 24, 2024 · Sorbitan tristearate finds application in various fat-based products, such as margarine, where it exerts a significant impact on the crystalline structure of the overall fat content. It belongs to the family of sorbitan fatty acid esters, which are derived from sorbitol, a sugar alcohol, and lauric acid, a saturated fatty acid. The surfactants were sorbitan monoesters, sorbitan monolaurate, monopalmitate, monostearate and monooleate, which differed from each other in the length or structure of the hydrocarbon Download scientific diagram | Chemical structure of polysorbates, (a) polyethylene glycol sorbitan monolaurate, Tween® 20, and (b) polyethylene glycol sorbitan monooleate, Tween® 80 from Tween ® 20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. 0% and NMT 45. PSs are used in numerous applications within biochemistry, food production, and cosmetics, as well as for pharmaceutical purposes. Tween 20 (Polyethylene glycol sorbitan monolaurate), or Polysorbate 20 is a non ionic detergent available as 100% research grade or as 10% proteomic grade detergent. It is used in a study to assess enhanced solubility and oral bioavailability of itraconazole. 0% and NMT 63. The chemical structure of Sorbitan monolaurate (Span 20) is a non-ionic food-grade emulsifier primarily obtained by esterification of lauric acid with sorbitan (a dehydrated sorbitol derivative). The physical manifestation of these chemical properties is its appearance as an amber to light brown oily liquid at room temperature. Polyethylene glycol 20 sorbitan ether monolaurate; Polyoxyethylene 20 sorbitan monododecanoate; Polyoxyethylene 20 sorbitan monolaurate [9005-64-5] Span® 20 for synthesis. The Polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate) Polysorbate 40 (polyoxyethylene (20) sorbitan monopalmitate) Polysorbate 60 (polyoxyethylene (20) sorbitan monostearate) Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate) The number following the 'polysorbate' part is related to the type of major fatty acid associated with the molecule. It is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid. Properties: Sorbitan Monolaurate (Span-20) is an amber-to-brown oily liquid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic Apr 11, 2024 · Span-20 - Standard Authoritative Data Verified Data This product is Sorbitan and monolauric acid ester mixture, sorbitol dehydration, in alkaline catalyst, and lauric acid esterification and prepared; or from sorbitol and lauric acid in 180 ~ 280T: under the direct esterification of the system. As an emulsifier and stabilizer, Sorbitan Laurate helps to blend water and oil-based ingredients in formulations, enabling uniform dispersion 5 days ago · Tween-20 is recommended for ELISA and immunoblots. The sorbitan backbone, with its hydroxyl groups, contributes the hydrophilic character, while the lauryl chain of lauric acid provides the lipophilic aspect. (Sorbitan monolaurate CAS 1338-39-2) Overview of Sorbitan Monolaurate Sorbitan Monolaurate is a highly effective surfactant and wetting agent that enhances the penetration and distribution of other ingredients in various formulations. Polysorbates 20 and 80 (Tween® 20 and Tween® 80) are used in the formulation of biotherapeutic products for both preventing surface adsorption and as stabilizers against protein aggregation. As the name Here, we report on the transport enhancing properties of mixtures of an anionic surfactant, sodium lauroylsarcosinate (NLS) and a non-ionic surfactant, sorbitan monolaurate (S20) in 1:1 phosphate Jan 6, 2025 · Sorbitan monolaurate is a small molecule drug. Sep 25, 2025 · Uses Sorbitan Monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. 24 Da. Span-20 HLB is 8. . The structural formula of sorbitan monolaurate is described in Jul 1, 2016 · Although non-ionic surfactants, such as sorbitan fatty acid esters and, especially, sorbitan monooleate, are excipients employed in a wide variety of nanotechnology-based products, they have been generally used in combination with other materials, such as different surfactants, oils or other lipids, rather than as a main ingredient. "Purity" relates to the observed percent of the ex Tween-20 is also known as Polyethylene glycol sorbitan monolaurate, Polysorbate 20, Sorbimacrogol Laurate 300, and Polyoxyethylenesorbitan monolaurate. The polysorbates are amphipathic, nonionic surfactants composed of fatty acid esters of polyoxyethylene sorbitan being polyoxyethylene sorbitan monolaurate for polysorbate 20 and polyoxyethylene sorbitan The most common polysorbates used as excipients are polysorbate 20 (polyoxyethylene sorbitan monolaurate) and polysorbate 80 (polyoxyethylene sorbitan monooleate). Jan 1, 1994 · PDF | Sorbitan ester surfactants are very complicated mixtures. Its unique properties enhance formulation stability and bioavailability, making it ideal for various applications. Examples of the use of PSs are as excipients in vaccines, emulsifiers or stabilization of Abstract: The heterocyclic compounds, mainly carbohydrate-based surfactant, 1, 4 Sorbitan, namely (Sorbitan Mono-stearate with 20 moles of Ethylene oxide SMS-20-EO, Sorbitan Mono-oleate SMO, and Sorbitan Mono-oleate ethoxylated with 20 moles of Ethylene oxide SMO-20-EO ) have been synthesized and characterized through different spectroscopic methods (FTIR, 1H NMR). Tween-20 is also known as Polyethylene glycol sorbitan monolaurate, Polysorbate 20, Sorbimacrogol Laurate 300 and Polyoxyethylenesorbitan monolaurate. ChemSpider record containing structure, synonyms, properties, vendors and database links for Sorbitan laurate, 1337-30-0, KCFFTRNUGSQDSY-BURFUSLBSA-N Nov 1, 2023 · The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. The ratio of the OH group to the (C11H23COO) group is mainly 3:1. Abstract Polysorbates 20 and 80 (Tween 20 and Tween 80) are used in the formulation of biotherapeutic products for both preventing surface adsorption and as stabilizers against protein aggregation. It is distinguished from other polysorbates due to the shortest length of the fatty acid and the highest HLB value. Aug 21, 2025 · Use of Span 20 Sorbitan monododecanoate is a sorbitan ester surfactant. The overall knowledge and encyclopedia of Polyoxyethylene sorbitan monolaurate covering characteristics, safety, Polyoxyethylene sorbitan monolaurate usage, MSDS/SDS and more. sorbitani lauras Span 20 (=Sorbitan Monolaurate) Definition and Chemical Structure The chemical name of Polysorbate 20 is Polyoxyethylene (20) sorbitan monolaurate. JFC Chemical Structure: A nonionic surfactant formed by the ethoxylation of sorbitan monolaurate, consisting of approximately 20 units of polyethylene glycol distributed across four chains. Feb 16, 2020 · Introduction Polyoxyethylene (20) sorbitan monoesters, also called polysorbates (PS), are non-ionic surfactants with several brand names such as Canarcel and Tween™. The polysorbates are amphipathic, nonionic surfactants composed of fatty acid esters of polyoxyethylene sorbitan being polyoxyethylene sorbitan monolaurate for polysorbate 20 and polyoxyethylene sorbitan monooleate for polysorbate 80. An improved and simple reversed phase high performance liquid chroma tographic (HPLC) | Find, read and cite all the research you laurate de sorbitan laurato de sorbitán sorbitan mono-laurate Sorbitan monolaurate, Sorbitan monododecanoate Sorbitan monolaurate, tech. Under esterification conditions and high temperature (>200 °C), sorbitol undergoes an internal dehydration reaction to give a tetrahydrofurane structure (sorbitan) that is esterified by the fatty acid mainly on the primary hydroxyl group (see Dec 26, 2023 · Sorbitan Monolaurate (Span 20) is also utilized in industrial processes such as the production of synthetic fibers and plastics. May 5, 2017 · Abstract The Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re-evaluating the safety of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives. Polyethylene glycol 20 sorbitan ether monolaurate; Polyoxyethylene 20 sorbitan monododecanoate; Polyoxyethylene 20 sorbitan monolaurate [9005-64-5]. ChemicalBook provide information on the 1338-39-2: structure, uses, msds, molecular formula, cas, and suppliers. Pharmaceutical excipients generally refer to inactive Sep 1, 2021 · Here, we present a method for preparing vesicles by combining hydrothermal emulsification with solvent diffusion (SD). Sorbitan Monolaurate is slightly soluble in isopropanol, tetracarp, xylene, cotton seed oil, and mineral oil and soluble in liquid paraffin and water. Its balanced hydrophilic–lipophilic nature makes it a versatile emulsifier Download scientific diagram | Nomenclature and molecular structure of sorbitan monooleate (SmO, commercial names: Span80 and Alkamuls S/80), sorbitan monolaurate (SmL, commercial names: Span20 and Selected chemical and physical parameters * the represented formula is simplified showing the structure of sorbitan laurate, only. 47 g/mol. Tween 20 (CAS No,: 9005-64-5) has many uses in biochemical applications, including washi The esterification of a liquid solution of sorbitol with fatty acids leads to a variety of mild tensioactive agents commonly known as sorbitan esters. Introduction Sorbitan esters, commonly known as Span, are nonionic surfactants. The polysorbates are amphipathic, nonionic surfactants composed of fatty acid esters of polyoxyethylene sorbitan being polyoxyethylene sorbitan monolaurate for polysorbate 20 and polyoxyethylene sorbitan Sorbitan monolaurate | C18H34O6 | CID 11046239 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. [1] Sorbitan monolaurate has been shown to act as an absorption enhancer, which may be due to its ability to form hydrogen bonds with other molecules and its capacity to interact with sodium citrate. Then estimated as corrosion ChemSpider record containing structure, synonyms, properties, vendors and database links for Sorbitan, monododecanoate, 1338-39-2, LWZFANDGMFTDAV-URHIDPGUSA-N Apr 15, 2011 · Polysorbate 20 (polyoxyethylene sorbitan monolaurate) and polysorbate 80 (polyoxyethylene sorbitan monooleate) are non-ionic surfactants commonly used in the formulation of protein pharmaceuticals. Get to learn about properities of Polyoxyethylene sorbitan monolaurate 9005-64-5. Uses sorbitan laurate is an emulsifier in cosmetic creams and lotions as well as a stabilizer of essential oils in water. A simplified representation of that network can be interactively explored below. ” The HLB value of sorbitan laurate is 8. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Its unique chemical structure allows it to lower surface tension and increase wettability, enabling better interaction and dispersion of active ingredients. Download scientific diagram | Chemical structure of sorbitan monolaurate (Span ? 20) from publication: Effect of mefloquine in the rheologic behavior of Soluplus® as a prior knowledge to hot melt Jan 9, 2004 · The effect of molecular structure of four sorbitan monoester surfactants (sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate and sorbitan monooleate) on the formation of simple three-component creams is presented. It has a molecular formula of C58H114O26. 0% of polyols (w/w). Specifications: Mar 23, 2023 · Origin PEG-80 Sorbitan Laurate is made through a chemical reaction between Sorbitan monolaurate and ethylene oxide, resulting in the formation of polyethylene glycol (PEG) chains attached to the sorbitan monolaurate molecule. Sorbitan monooleate [1338-43-8]. If generated, an InChI string will also be generated and made available for searching. » Sorbitan Monooleate is a partial oleate ester of Sorbitol and its mono- and dianhydrides. It consists of a hydrophilic (water-loving) polyoxyethylene chain and a hydrophobic (oil-loving) fatty acid (lauric acid, C12). Span-20 is slightly soluble in isopropanol, tetracarp, xylene, cottonseed oil, and mineral oil, slightly soluble in liquid paraffin, and insoluble in water, HLB=8. Non-toxic and odorless. Polysorbate 20, also known as polyoxyethylene (20) sorbitan monolaurate. Its main purpose is to serve as an emulsifier, ensuring the proper blending of water and oils. Substance record SID 134979486 for Sorbitan monolaurate [USAN:NF] submitted by ChemIDplus. Assay for fatty acids— Transfer about 10g of Sorbitan Monolaurate,accurately weighed,to a 500-mLconical flask,cautiously add 100mLof alcohol and 3. It is currently authorised in the European Union and it is intended t Sorbitan monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. Jun 30, 2020 · The additive sorbitan monolaurate consists of sorbitol (and its anhydrides) esterified with fatty acids derived from coconut oil. It consists of sorbitol, ethylene oxide, and lauric acid. Discrimination of polysorbate 20 by high-performance liquid chromatography-charged aerosol detection and characterization for components by expanding compound database and library Commercial products may be mixtures of fatty acid esters of 1,4- and 1,5 anhydrosorbitol and 1,4,3,6-dianhydrosorbitol, but generally conform to the structure depicted below. The numbers following Span denote different fatty acids: for example, Span 20 represents sorbitan monolaurate, Span 40 represents sorbitan monopalmitate, Span 60 represents sorbitan monostearate, and Span 80 represents sorbitan monooleate. Sorbitan monolaurate also has biological properties such as the inhibition of autoimmune diseases, malonic acid production, and bacterial growth. Its stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications. CAS 1338-39-2, molar mass 346. 6. Sorbitan monostearate, also referred to as Span 60TM or a synthetic wax, is an ester derived from sorbitan (a derivative of sorbitol) and stearic acid. The polysorbates are amphipathic, nonionic surfactants composed of fatty acid esters of polyoxyethylene sorbitan being polyoxyethylene sorbitan monolaurate for polysorbate 20 and polyoxyethylene Feb 5, 2010 · The values on the first two rows are based on the spectra depicted in Fig. Sorbitan forms the central part of the molecule, linked with lauric acid, imparting lipophilic characteristics, allowing it to mix well with oils and other non-polar substances. Sorbitan laurate is a common component in laundry products, cleaners, aerosol sprays, disinfectants, pest control sprays, polishes, water softeners, coatings, paints, thinners, paint removers and cosmetics. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar The ratio of the OH group to the (C11H23COO) group is mainly 3:1. Sorbitan laurate; INS No. It takes its name from an ethoxylation process which leaves the molecule with 20 repeat units of polyethylene glycol. At room temperature, it is Apr 19, 2025 · This study investigates the correlation between the hydrophilic–lipophilic balance (HLB) values and the π–A isotherm parameters of surfactant monolayers composed of sorbitan esters, specifically sorbitan monopalmitate, sorbitan tristearate, sorbitan monooleate, and sorbitan sesquioleate. Sorbitan monolaurate has a monoisotopic molecular weight of 346. ” The formulation and characterization of a novel anhydrous organogel formulated as a potential delivery vehicle from a solution of 2 nonionic surfactants, sorbitan monostearate (Span 60) and polysorbate 20 (polyoxyethylene sorbitan monolaurate; Tween 20), in hexadecane at 60DGC, which cools to a white, semi-solid, thermoreversible gel at room temperature, are described. Download scientific diagram | (I) Chemical structure of major expected POE esters in polysorbates, the polysorbates are mainly composed of fatty acid esters sharing common sorbitan or isosorbide 1 sorbitan and lauric acid as the primary fatty acid. The addition of an Oct 23, 2025 · Polysorbate 20 (CAS 9005-64-5) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices 5 days ago · Sorbitan monolaurate, CAS: 1338-39-2, is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. The data are manually curated and of the highest quality. Polysorbate 20 mber 1, 2014 . These compounds are integral in forming water-in-oil (W/O) emulsions, making TWEEN® 20 Low-peroxide; Low-carbonyls; CAS Number: 9005-64-5; Synonyms: Polyethylene glycol sorbitan monolaurate,Polyoxyethylenesorbitan monolaurate at Sigma-Aldrich [Graphic formula same as for Sorbitan Monolaurate, except that R is (C 17 H 33)COO. 85544 Span® 20 Synonym (s): Sorbitan monolaurate, Span® 20 Photos (1) Sign In to View Organizational & Contract Pricing Sorbitan monostearate is an ester of sorbitan (a sorbitol derivative) and stearic acid and is sometimes referred to as a synthetic wax. The role of polysorbate in protein formulations is to prevent the formation of aggregates [1], [2] and protect the protein from denaturation at liquid-vial and liquid-air interfaces [3]. Cited in 1 publications Properties: Span-20 (Sorbitan Monolaurate) is an amber to brown oily liquid. Laureate: Sorbitan monolaurate is a mixture of esters formed from the fatty acid lauric acid and polyols derived from sorbitol, including sorbitan and isosorbide. Polysorbate 20 (C ₁₉ H ₃₇ O ₅) is an ethoxylated sorbitan monolaurate. 6, facilitating the dispersion of oil in water phases. brand name Span 20 (ICI Americas). Proceed as directed in the Assay for fatty acids under Sorbitan Monooleate,beginning with “Connect a suitable condenser. - Find MSDS or SDS, a COA, data sheets and more information. It belongs to the sorbitan ester family, offering amphiphilic properties that enable the formation of stable oil-in-water and water-in-oil emulsions. General Polysorbate 20 (common commercial brand names include Kolliphor PS 20, [2] Scattics, Alkest TW 20, Tween 20, and Kotilen-20) is a polysorbate -type nonionic surfactant formed by the ethoxylation of sorbitan monolaurate. Sorbitan monolaurate is defined as a polyoxyethylene sorbitan derivative with the empirical formula C58H114O26, commonly used as an emulsifier, particularly in food wraps, and characterized by its oily liquid state and solubility in water. Sorbitan Monolaurate Sorbitan, esters, monododecanoate; Sorbitan monolaurate [1338-39-2] DEFINITION Sorbitan Monolaurate is a partial ester of lauric acid with Sorbitol and its mono- and dianhydrides. For example, the desired anhydro sorbitol for making a sorbitan monolaurate surfactant has a hydroxyl number in the range of about 1150 to about 1250, while the desired anhydro sorbitol for making a sorbitan monostearate surfactant has a hydroxyl number in the range of about 1250 to about 1400. ezaii dag bhvvs ysxx60eg 8aigac k2ics an t5nn 1pxu hxuekf