Syringocystadenoma papilliferum vulva. Syringocystadenoma papilliferum is a rare (in the vulva) benign adnexal lesion of hamartomatous origin that is often seen in children and adolescents. " by Kayla Bagwell et al. It was launched in 2003 by Dr. 2 Mar 15, 2002 · Abstract Syringocystadenoma papilliferum (SP) commonly arises in conjunction with nevus sebaceous. To date, only 17 cases of their coexistence have been reported worldwide. Typically, the epidermis will show one or more cystic invaginations (right) which extend downward into the dermis. Expand 15 1 Excerpt Oct 10, 2020 · Syringocystadenoma Papilliferum (SCAP) is a benign hamartomatous adnexal tumor of the apocrine or eccrine sweat glands. Although it is rare, the association of tubular apocrine adenoma with syringocystadenoma papilliferum developing in a sebaceous nevus on the scalp is well documented. 4 days ago · Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant adnexal tumor of apocrine origin, most commonly arising in the head and neck regions. anogenital area) of females. We present a first case of SCAP developing at vaginal vault in 35-year-old Apr 6, 2024 · Syringocystadenoma papilliferum is a benign cutaneous adnexal tumor of eccrine and apocrine glands, with a warty appearance that is usually found on the scalp, neck and face, much less frequently appears in the chest or abdomen and extremely rarely on the female genital organs, i. It usually presents as papule plaques or nodule on head and neck. [2] These hidradenomas are sharply circumscribed, nodular tumors that usually develop in women's anogenital area (particularly the vulva [3]) but ABStrACt Syringocystadenoma papilliferum is also known as papillary syringadenoma. This condition predominantly manifests in regions such as the head, face, neck, and trunk. To subscribe or unsubscribe to Case of the Month or our other email lists, click here. Choice D may suggest an invasive focus within the neoplasm, given the absence of myoepithelial layer around some tubular structures. It is most commonly found in the vulva, perianal area, and perineum but can occasionally occur in the nipples, eyelids, and external auditory canal. In a recent review [28], hidradenoma papilliferum was the most common benign vulvar glandular neoplasm accounting for 60 % of the benign lesions. Aug 1, 2013 · Syringocystadenoma papilliferum (SCP) is a rare, benign, adnexal tumour of apocrine or eccrine differentiation. [1] Mar 13, 2019 · The histologic differential diagnosis includes syringocystadenoma papilliferum and tubular apocrine adenoma. In general, the diagnosis can be reached due to the location of the tumor, female gender, lack of a lymphoplasmacytic infiltrate or epidermal connection. , 2007). Aug 5, 2024 · Tubular apocrine adenoma is a benign dermal adnexal neoplasm of apocrine derivation and is associated with organoid nevus, nevus sebaceus of Jadassohn and syringocystadenoma papilliferum (SCAP). Hidradenoma papilliferum, also called papillary hidradenoma, is benign tumour arising from apocrine glands (see sweat gland lesions). Parks A, Drake K, Metcalf J, Underwood P et al. Complete excision Jan 1, 2024 · Syringocystadenoma papiliferum (SCAP) is an infrequent, benign neoplasm originating from the apocrine or, less frequently, eccrine sweat glands. It usually develops on the scalp and is associated with a nevus sebaceus in 40% of cases. Jan 24, 2023 · Skin nonmelanocytic tumor - Syringocystadenoma papilliferum is a benign, hamartomatous, adnexal tumor that originates from the apocrine or the eccrine sweat glands We present a case of Syringocystadenoma papilliferum on the vulva of a 64-year-old woman. This case Jan 1, 2024 · Syringocystadenoma Papilliferum of the Vulva: An Extremely Rare Vulvar TumorJ Low Genit Tract Dis. References Syringocystadenoma Papilliferum (SCAP) is a rare benign tumor primarily occurring in the head and neck region. literature we identified only 5 such lesions previously reported on the vulva. [2-6] Duran M, Ustunyurt E, Turgut A, Yeşildağlar N. This case illustrates the atypical location of this rare disease and adds to the differential diagnosis of lesions on the vulva. An excision biopsy was performed under general anaesthesia and the INTRODUCTION Syringocystadenoma papilliferum (SCAP) is an uncommon benign skin adnexal tumour that was first described by Stokes in 1917 as naevus syringoadenomatosus papilliferus. Syringocystadenoma Papilliferum in an Unusal Location on Vulva: A Case Report. Only few cases reported in the literature. When congenital, SCAP is frequently associated with nevus sebaceous of Jadassohn. 9 may differ. 13,14 It would seem that such lesions do not differ from MLG adenomas with a surface connection. SUMMARY A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . Stewart Medicine Pathology 2008 TLDR A case with similar features recently encountered in the authors' department, a 27-year-old with paraplegia and a history of repetitive peri-urethral trauma related to self-catheterisation, is presented. Syringocystadenoma papilliferum is a rare, benign adnexal neoplasm originating from apocrine or eccrine sweat glands. Examination revealed a polypoid cystic lesion with n … Introduction Hidradenoma papilliferum (HP) is a rare benign tumor of the vulva, perineum, and perianal skin, in particular the vulvar interlabial sulcus and, much less commonly, “ectopic” sites. We report here an 18-year-old girl who had linear syringocystadenoma papilliferum in the pubic 18 February 2015 - Case #343 All cases are archived on our website. This is a warty tumour of the scalp, neck and face that occurs at any age. Jun 1, 2009 · Hidradenoma papilliferum (HP) of the anogenital region, which was previously thought to be an apocrine tumour, is now believed to be derived from anogenital mammary-like glands (MLG) and is more accurately termed MLG adenoma. This tumor is usually seen on the lower eyelids and Hidradenoma papilliferum is an uncommon benign tumour that is located in the anogenital region of middle-aged women. Syringocystadenocarcinoma papilliferum (SCACP) is an extremely rare malignant adnexal tumor, which arises from syringocystadenoma papilliferum. To view them sorted by case number, diagnosis or category, visit our main Case of the Month page. 2024 Jan 1;28 (1):107-109. 561 Die− se gehen jedoch im Unterschied zum HP von der Epidermis aus und erklären die verruköse oder auch ulzerierte Tumoroberflä− che. We report the case of an 18‐year Nov 9, 2024 · Syringocystadenoma papilliferum is a rare benign adnexal tumor that frequently shows apocrine differentiation. Mar 28, 2025 · Papilliferous syringocystadenoma is a rare cutaneous adnexal tumor, described in the literature as benign and of hamartomatous origin, although the underlying mechanisms are not fully understood. Gynaecological assessment has to be performed to exclude potential for malignancy. Histogenesis of the tumor is still unclear. Nov 29, 2023 · The clinical & pathological characteristics, immune profile, histological occurrence, diagnosis, & differential diagnosis of vulvar hidradenoma papilliferum. Nishie, Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands, J Cutan Pathol, № 31, с. We present a case of Syringocystadenoma papilliferum with papulonodular lesion located on the vulva of an infant girl. Sep 29, 2023 · A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . Examination revealed a polypoid cystic lesion with no regional lymphadenopathy. —In this retrospective review, we identified several benign entities that have not been previously reported on the vulva, namely pilomatricoma, poroma, spiradenoma, and sebaceoma. SCACP lesions appear as raised nodules or inflammatory Mar 1, 2018 · Request PDF | On Mar 1, 2018, J. In 50% of cases, lesion is present since birth or early childhood; in another 15–30% cases, it develops during puberty [1]. SCAP can present atypically in the vulva, as demonstrated in a 45-year-old case study. 9 - other international versions of ICD-10 D23. Ein gemeinsames Auftreten eines HP mit Merkmalen des Syringocystadenoma papilliferum wurde kürzlich bei einem Tu− mor der Vulva beschrieben [4]. (2003) Syringocystadenoma papilliferum arising on the scrotum. We sought to explore any ramifications that may have resulted from the perceived change in histogenesis of this tumour. The epidermis typically exhibits a reactive papillary hyperplasia and merges with the underlying glandular epithelium, which is reminiscent of hidradenoma, with a discrete population of basal Mentioning: 6 - A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . . Summary Syringocystadenoma papilliferum usually presents as a solitary papule, nodule, or plaque on the scalp, and, in many cases, the lesion is associated with a nevus of Jadassohn. e. A 16-year-old female patient presented with multiple linearly arranged pink pedunculated grouped papules and plaques with irregular and lobulated surfaces present over the hypogastrium region for 6 years. An excision biopsy was performed under general anaesthesia and the ICD 10 code for Benign neoplasm of vulva. Abstract Introduction. The patient presented with a single cystic lesion on the left labia minora of 8 years duration Syringocystadenoma papilliferum (SCAP) may be present at birth (50% of cases) or develop around puberty (15-30% of cases). It is characterized by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium. The patient presented with a single cystic lesion on the left labia minora of 8 years duration with a recent increase in size and redness around the lesion. Excisional biopsy is a definitive method of treatment. Syringocystadenoma papilliferum occurs alone or in association with other tumors. This feature can be helpful in distinguishing SP from hidrandeoma papilliferum (helpful hint: Syringocystadenoma papilliferum opens up to the Jan 6, 2016 · Presentation outside the head and neck region is even more uncommon. May 29, 2020 · Syringocystadenoma papilliferum is a benign hamartomatous tumor of skin appendages. May 28, 2014 · A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . C. It is frequently seen in association with other benign adnexal lesions, such as nevus sebaceous, apocrine nevus, tubular apocrine adenoma, apocrine hidrocystoma, apocrine cystadenoma, and clear cell syringoma. Syringocystadenoma papilliferum in the vulvar region is a rare condition presenting as papule lesion in the age group of 27–64 years. Papillary fronds extend upward from the base, while plasma cells are common in the core of each frond. Sir, I read with interest the report by Tseung and Russell of breast-like vulval lesions, particularly the case that exhibited areas resembling syringocystadenoma papilliferum (SP), and would Syringocystadenoma papilliferum is a rare, hamartomatous benign tumor originating from either the eccrine or apocrine sweat glands. The patient presented with a single cystic lesion on the left labia minora of 8 years duration with a Feb 3, 2022 · Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant neoplasm arising from adnexal tissues and is the malignant complement to the benign neoplasm syringocystadenoma papilliferum (SCAP). , Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands: report of a case and review of the literature, Am J Dermatopathol 2012; 34:104-9. We present the case of A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . SCAP typically presents as slow developing, non-specific, smooth, skin-colored to pink papule, verruca or nodule, which may be exudative. Clinically, SCACP appears as a nodule, inflammatory plaque, or tumor. To date, less than 30 cases of malignant SCACP have been reported, of which locoregional metastases were found in only four cases. For a long time, it was thought to be a benign tumor of apocrine origin. It was subsequently expanded to include other organ systems. Choice C is a feature of syringocystadenoma papilliferum. We present a 43-year-old female with a non-anogenital (ectopic) hidradenoma papilliferum on her nose. Syringocystadenoma papilliferum and tubular apocrine adenoma are rare benign sweat gland tumors. The epidermis typically exhibits a reactive papillary hyperplasia and merges with the underlying glandular epithelium, which is reminiscent of hidradenoma, with a discrete population of basal Introduction Hidradenoma papilliferum is a rare benign tumor that occurs in the skin, primarily affecting women during their reproductive years. We report the second case of verrucous carcinoma in conjunction with SP. Malignant sweat gland tumours of the vulva are very rare. The patient presented with a single cystic lesion on the left labia minora of 8 years duration with a Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant adnexal neoplasm, which is considered as a malignant counterpart of syringocystadenoma papilliferum (SCAP). Lesions are asymptomatic, appearing as skin-colored to pink papules or plaques on the head and neck. KEY WORDS: Hidradenoma papilliferum, labia majora, syringocystadenoma papilliferum, trichoepithelioma Introduction Hidradenoma papilliferum (HP) is a rare, benign tumor of apocrine gland that typically presents in the anogenital region of 30–49-year-old females. Oct 31, 2011 · Hidradenoma papilliferum is a rare benign neoplasm that usually occurs in the female anogenital area. Sep 1, 2013 · Conclusions. Vulvar syringoma, on the other hand, is an e … Syringocystadenoma papilliferum is rare nonmalignant adnexal sweat gland neoplasm characterized by asymptomatic, skin colored to pink papules, or plaques of highly variable appearance. Examination revealed a polypoid cystic lesion with Syringocystadenoma papilliferum is a benign cutaneous adnexal tumor of eccrine and apocrine glands, with a warty appearance that is usually found on the scalp, neck and face, much less frequently appears in the chest or abdomen and extremely rarely on the female genital organs, i. 9 Hidradenoma papilliferum similarly differenti-ates towards the secretory portion of the sweat gland but is more common on the vulva, breast, or eyelid, and unlike SCAP, there is no epidermal connection with hidradenoma papilliferum (it May 21, 2021 · Choice B is a cardinal feature of so called aggressive digital papillary adenocarcinoma. Most patients present a solitary lesion in the head and neck region. Mar 13, 2023 · Cystic invaginations extending downward from the epidermis along with plasma cell infiltration are characteristic of histological findings of syringocystadenoma papilliferum and the absence of connection in the papillary structure distinguishes hidradenoma papilliferum from syringocystadenoma papilliferum. Histopathologically, the lesion appears as a crateriform lesion, composed of one or several dilated and confluent hair follicle infundibula connected with numerous papillary structures. 1 It typically develops from its benign precursor, syringocystadenoma papilliferum (SCAP), which often presents as a slow-growing, verrucous lesion for many years. Most common sites are head and neck region; however, tumor in other areas, such as vulva, external ear, lower leg, and scrotum, have also been reported. The lesion is a small solitary dermal or subcutaneous nodule, most commonly on the vulva. Syringocystadenoma papilliferum is defined as a distinctive lesion that typically occurs in the head and neck region, primarily the scalp, presenting as a solitary plaque or nodule, often in children. Syringocystadenoma papilliferum (SP) is a well-delineated lesion composed of interconnected papillary fronds and duct-like structures. [1] Syringocystadenoma papilliferum or papillary syringocystadenoma is found on head and neck, often in association with sebaceous naevus Hidradenoma papilliferum or papillary hidradenoma is found on the vulva or perianal skin and is now thought to be derived from mammary-like cells Syringocystadenoma papilliferum of the vulva has been reported associated with HP. J Clin Anal Med 2013;4(suppl 4): 392-3. 1097/LGT. Jan 3, 2022 · Hidradenoma papilliferum is a benign dermal papulonodular tumor almost always found in the vulva / perianal region of women Abstract Syringocystadenoma papilliferum is a rare benign hamartomatous adnexal tumor of the apocrine or eccrine sweat glands. We report a case of a 30-year-old female who presented with a 10-year history of an asymptomatic, slow-growing scalp We report a rare case of syringocystadenoma papilliferum (SCAP) presenting as multiple papulonodules in a linear pattern over right lower abdomen which has been reported only once before. There Apr 2, 2020 · A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . The patient had had a skin-colored subcutaneous Syringocystadenoma papiliferum (SCAP) is an infrequent, benign neoplasm originating from the apocrine or, less frequently, eccrine sweat glands. This tumor is usually seen on the lower eyelids and cheeks. Syringocystadenoma papilliferum rarely presents on the vulva and can be grossly indistinguishable from other vulvar pathology, necessitating histopathology for accurate diagnosis. This case illustrates the atypical location of this adnexal tumor and adds to the differential diagnosis of lesions on the vulva. the vulva. We present a case of Syringocystadenoma papilliferum on the vulva of a 64-year-old woman. The tumour appears " de novo " or may arise Syringocystadenoma papilliferum is a very rare, benign adnexal tumor that originates from the apocrine sweat glands. Jan 1, 2013 · The syringocystadenoma papilliferum is a benign rare adnexal skin neoplasm with different clinical presentations , namely papules, nodules or plaques. This case Jul 30, 2018 · We reported a case of Syringocystadenoma papilliferum with sessile nodular lesion located on the vulva of an 49 yr old female. Presentation outside the head and neck region is even more uncommon. Comment Here Reference: Papillary eccrine adenoma Tubular apocrine adenoma (TAA) and syringocystadenoma papilliferum (SCAP) are rare benign sweat gland tumors. 9 became effective on October 1, 2025. Mouna Khmou, University Hospital CHU IBN SINA, Children's Hospital (Morocco), for contributing this case. Am J Dermatopathol 23: 87-89 Castilla EA et al. Microscopic Features: Hidradenoma papilliferum presents as a solid, well-demarcated nodule in the dermis or lamina propria. (2002) Trichilemmoma and syringocystadenoma papilliferum arising in naevus sebaceous. A papillary hidradenoma, also termed hidradenoma papilliferum or mammary-like gland adenoma of the vulva, [1] is a rare, but nonetheless most common benign tumor that occurs in and between anal and genital regions (i. A 57-year-old female patient who presented to our Oncology Department with a Sep 1, 2021 · The vulva refers to the external female genitalia and includes the mons pubis, labia majora, labia minora, clitoris, vulvar vestibule, urethral meatus, vaginal introitus, and Bartholin's and Skene's vestibular glands (Nguyen and Duong, 2020). Notably, it is frequently associated with hamartomas of endocrine, sebaceous, or follicular origin, as well as with sebaceous nevi. It is most commonly found in the vulva, perianal area, and perine Nov 1, 2008 · Request PDF | On Nov 1, 2008, Colin J R Stewart published Syringocystadenoma papilliferum-lik lesion of the vulva | Find, read and cite all the research you need on ResearchGate Vulvar dermatology represents a challenge for many providers. They are usually only diagnosed after excision and are thought to arise from anogenital mammary-like glands. Nov 11, 2014 · Therefore, the term “mammary-like gland adenoma of the vulva” has been proposed; however, hidradenoma papilliferum is best conceptually compared to intraductal papilloma of the breast [4, 27]. The overlying epidermis is normal, acanthotic, or ulcerated. Syringocystadenoma papilliferum-like lesion of the vulvaMeSH terms Adult Female Humans Immunohistochemistry Paraplegia / complications Receptors, Estrogen / metabolism Receptors, Progesterone / metabolism Urinary Catheterization Vulvar Diseases / complications Vulvar Diseases / metabolism Vulvar Diseases / pathology* Jul 6, 2009 · Sir,I read with interest the report by Tseung and Russell of breast-like vulval lesions, particularly the case that exhibited areas resembling syringocystadenoma papilliferum (SP),1 and would like Syringocystadenoma papilliferum is a benign cutaneous adnexal tumor of eccrine and apocrine glands, with a warty appearance that is usually found on the scalp, neck and face, much less frequently appears in the chest or abdomen and extremely rarely on the female genital organs, i. These papillae are lined by Aug 20, 2024 · Boni R et al. That said, vulvar lesions can often Syringocystadenoma papilliferum is a rare benign adnexal tumour which originates from the apocrine or the eccrine sweat glands and various malignancies like basal cell carcinomas, squamous cell carcinoma and ductal carcinoma have been documented to arise in SP. Notably, it Duran M, Ustunyurt E, Turgut A, Yeşildağlar N. Es tritt meist an Kopf, Gesicht oder Hals auf und kann bei etwa einem Drittel der Fälle mit einem Talgdrüsennaevus assoziiert sein. doi: 10. : While rare, syringocystadenoma papilliferum may occur d be mistaken for condyloma on gross physical examination. The histopathology, esentation, and reported cases. D23. The 2026 edition of ICD-10-CM D23. Excisional biopsy demonstrated the histological picture of syringocystadenoma papilliferum. Syringocystadenoma papilliferum (SP) is a rare benign adnexal tumour which originates from the apocrine or the eccrine sweat glands We present a case of Syringocystadenoma papilliferum with papulonodular lesion located on the vulva of an infant girl. Key words: mamary-like glands, syringocystadenoma papilliferum, hidradenoma papilliferum. Jeong and others published Syringocystadenoma papilliferum on the vulva | Find, read and cite all the research you need on ResearchGate Nov 1, 2021 · Examples of benign apocrine neoplasms include syringocystadenoma papilliferum and hidradenoma papilliferum, with syringocystadenocarcinoma and apocrine carcinoma representing their malignant counterparts (Obaidat et al. An excision biopsy was performed under general Papilliferous syringocystadenoma is a rare cutaneous adnexal tumor, described in the literature as benign and of hamartomatous origin, although the underlying mechanisms are not fully understood. This case WebPathology is an educational resource with high quality pathology images of benign and malignant neoplasms and related entities. Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis. 0000000000000754. Here, the authors present case series of eight cases, four male and four female patients, with varied presentations at different sites: scalp,upper Jan 1, 2024 · Syringocystadenoma papilliferum is a rare benign adnexal skin tumor of apocrine or eccrine glands. This case was reviewed Feb 26, 2024 · Hidradenoma papilliferum is a rare benign tumor that occurs in the skin, primarily affecting women during their reproductive years. We communicate the case of patient with a lesion to the vulva, which showed histological features of syringocystadenoma papilliferum overlapped with clinical and histological features of hidradenoma papilliferum. These lesions usually have an adjacent nevus sebaceous or adjacent basal cell carcinoma. 9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. It is commonly located on head and neck region. Sep 12, 2024 · Das Syringocystadenoma papilliferum, kurz SCAP, ist ein gutartiger Hauttumor mit apokriner Differenzierung. An excision biopsy was performed under general anaesthesia and the Jan 1, 2018 · Syringocystadenoma papilliferum is a rare (in the vulva) benign adnexal lesion of hamartomatous origin that is often seen in children and adolescents. Hidradenoma papilliferum and extramammary Paget disease were the most common benign and malignant adnexal neoplasms, respectively. The interest of this report lies in the rarity of syringocystadenoma papilliferum, its unusual presentation in the vulva, and it’s association with neurofibromatosis type 1. To our knowledge, this association has not been described in the medical Abstract Syringocystadenoma papilliferum (SCAP) is an uncommon benign adnexal tumor of the skin. Herein, we report a 25-year-old male who presented with a 10-year history of an asymptomatic slowly growing skin lesion on his face. Case Report. Get free rules, notes, crosswalks, synonyms, history for ICD-10 code D28. Histology of hidradenoma papilliferum Hidradenoma papilliferum is a well- circumscribed dermal nodule, usually without connection to the overlying epidermis (figure 1 A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . This is the American ICD-10-CM version of D23. Pathology 34: 196-197 Goshima J et al. The lesion is usually covered with crusts, which are formed by secretion of the apocrine epithelial May 9, 2016 · Papillary hidradenoma, also hidradenoma papilliferum, is a benign lesion typically found in the vulva. A case of syringocystadenoma papilliferum of the vulva in a 36-year-old woman is reported . As both a gynecologic and dermatologic organ, the vulva lies well within the purview of the dermatologist's practice. Dharam Ramnani, with an initial focus on urologic pathology. A case with similar features recently encountered in the authors' department, a 27-year-old with paraplegia and a history of repetitive peri-urethral trauma related to self-catheterisation, is presented. It is relatively rare to find outside the head and neck region and uncommon May 15, 2024 · A papillary hidradenoma, also known as a mammary-like gland adenoma of the vulva or hidradenoma papilliferum is a benign tumor that is most commonly found in females between the anal and genital regions or the anogenital area. Semantic Scholar extracted view of "Syringocystadenoma Papilliferum of the Vulva: An Extremely Rare Vulvar Tumor. The unusual reported locations of SCAP include the head and neck, the buttock, the vulva WebPathology is an educational resource with high quality pathology images of benign and malignant neoplasms and related entities. Given that the vulva is both a gynecologic and dermatologic organ, patients with cutaneous lesions involving the vulva may present to primary care, gynecology, or dermatology. (2001) Syringocystadenoma papilliferum: a study of potential tumor suppressor genes. [1] The scalp and face are the most common sites, but less frequently other sites can be involved – eyelid, scrotum, vulva, thigh and breast. Syringocystadenoma papilliferum-like lesion of the vulva. Other less common lesions reported with SP include apocrine adenoma, condyloma acuminatum, hidradenoma papilliferum associated with hidrocystoma, poroma folliculare, and a single case of verrucous carcinoma. 0. Thanks to Dr. dp2wr beew4q5 xwpjn03e jua 0ve3 pyesl7e 8mcs kk of8xp 0q